Synthesis of Unsymmetrical Heterobiaryls Using palladium-catalyzed cross-coupling reactions of lithium organozincates

نویسندگان

  • Anne Seggio
  • Anny Jutand
  • Ghislaine Priem
  • Florence Mongin
چکیده

Several unsymmetrical heterobiaryls have been synthesized through palladium-catalyzed cross-coupling reactions of lithium triorganozincates. The latter have been prepared by deprotonative lithiation followed by transmetalation using non hygroscopic ZnCl2·TMEDA (1/3 equiv).

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تاریخ انتشار 2017