Total synthesis of the natural product EBC-329.

نویسندگان

  • Raju S Thombal
  • Vrushali H Jadhav
چکیده

The first total synthesis of an anti-leukemic diterpene natural product EBC-329 (1) has been accomplished starting from readily available 6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione (7). An efficient and general approach has been reported for the synthesis of EBC-329 in 13 steps with an overall yield of 10%.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 36  شماره 

صفحات  -

تاریخ انتشار 2015