Glycolytic intermediates induce amorphous calcium carbonate formation in crustaceans.

نویسندگان

  • Ai Sato
  • Seiji Nagasaka
  • Kazuo Furihata
  • Shinji Nagata
  • Isao Arai
  • Kazuko Saruwatari
  • Toshihiro Kogure
  • Shohei Sakuda
  • Hiromichi Nagasawa
چکیده

It has been thought that phosphorus in biominerals made of amorphous calcium carbonate (ACC) might be related to ACC formation, but no such phosphorus-containing compounds have ever been identified. Crustaceans use ACC biominerals in exoskeleton and gastroliths so that they will have easy access to calcium carbonate inside the body before and after molting. We have identified phosphoenolpyruvate and 3-phosphoglycerate, intermediates of the glycolytic pathway, in exoskeleton and gastroliths and found them important for stabilizing ACC.

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عنوان ژورنال:
  • Nature chemical biology

دوره 7 4  شماره 

صفحات  -

تاریخ انتشار 2011