Long - term , but not transient , threshold shifts alter the 1 morphology and increase the excitability of cortical pyramidal 2 neurons 3 4
نویسندگان
چکیده
Long-term, but not transient, threshold shifts alter the 1 morphology and increase the excitability of cortical pyramidal 2 neurons 3 4 Sungchil Yang, Wendy Su and Shaowen Bao 5 6 Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720. 7 8 9 10 11 12 13 14 15 Running title: Hearing loss changes neuronal morphology and excitability 16 17 18 19 Total number of pages: 24 20 Total number of words in the text file: 6106 21 Total number of figures: 4 22 Total number of tables: 0 23 24 25 26 27 28 29 30 31 Correspondence to: Shaowen Bao, Ph.D. 32 Helen Wills Neuroscience Institute 33 University of California 34 Berkeley, CA 94720-3190 35 E-mail: [email protected] 36 Phone: (510) 643-3549 37 38 Articles in PresS. J Neurophysiol (June 20, 2012). doi:10.1152/jn.00371.2012
منابع مشابه
Long-term, but not transient, threshold shifts alter the morphology and increase the excitability of cortical pyramidal neurons.
Partial hearing loss often results in enlarged representations of the remaining hearing frequency range in primary auditory cortex (AI). Recent studies have implicated certain types of synaptic plasticity in AI map reorganization in response to transient and long-term hearing loss. How changes in neuronal excitability and morphology contribute to cortical map reorganization is less clear. In th...
متن کاملAction of brain-derived neurotrophic factor on function and morphology of visual cortical neurons
Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...
متن کاملAction of brain-derived neurotrophic factor on function and morphology of visual cortical neurons
Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...
متن کاملAntibiotic Supplements Affect Electrophysiological Properties and Excitability of Rat Hippocampal Pyramidal Neurons in Primary Culture
Introduction: Antibiotic supplements are regularly used in neuronal culture media to control contamination however, they can interfere with the neuronal excitability and affect electrophysiological properties. Therefore, in this study, the effect of penicillin/streptomycin supplements on the spontaneous electrophysiological activity of hippocampal pyramidal neurons was examined. Methods: Electr...
متن کاملThe Effect of Noise Pollution Exposure during Pregnancy on Long Term Potentiation Induction in Pyramidal Neurons of Hippocampus CA1 area in Male Rat Offsprings
Background: It is believed that cognitive processing is easily disturbed by incompatible environmental stimulations. Many studies have shown that prenatal stress affects fetal brain development. The aim of this study was to evaluate the effect of noise pollution exposure during conception period on neural activity of hippocampus CA1 area in male rat offspring. Methods: Four groups of rats inclu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012