7T versus 3T phosphorous magnetic resonance spectroscopy in patients with dilated cardiomyopathy
نویسندگان
چکیده
Background Phosphorous magnetic resonance spectroscopy (PMRS) allows insight into cardiac energetics in vivo, but it is a technique with an intrinsically low signal to noise ratio (SNR). The 2.4x increased SNR, that is predicted by theory at 7T compared to 3T, should allow detection of smaller changes in metabolite concentrations or measurement of changes in smaller patient groups, which will further our understanding of cardiac energetics. This study represents the first cardiac P-MRS patient data acquired at a 7 Tesla field strength.
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Human cardiac 31P magnetic resonance spectroscopy at 7 tesla
PURPOSE Phosphorus magnetic resonance spectroscopy ((31)P-MRS) affords unique insight into cardiac energetics but has a low intrinsic signal-to-noise ratio (SNR) in humans. Theory predicts an increased (31)P-MRS SNR at 7T, offering exciting possibilities to better investigate cardiac metabolism. We therefore compare the performance of human cardiac (31)P-MRS at 7T to 3T, and measure T1s for (31...
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