Prolonged elevation of serum tryptase resulting from intraoperative anaphylaxis to methylene blue
نویسندگان
چکیده
Background Intraoperative anaphylaxis during sentinel lymph node biopsy is a well known phenomenon occurring with administration of patent blue and isosulfan blue dyes, with an incidence of 2.2% and 1.1%, respectively (1,2). Methylene blue has been reported as being a safer alternative with only a few case reports demonstrating anaphylaxis and large studies demonstrating no incidence of anaphylaxis in 224 patients (3,2).
منابع مشابه
Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy
BACKGROUND Lymphazurin 1% blue dye can cause a severe anaphylactic reaction in approximately 1-3% of patients. CASE PRESENTATION We describe a case of intraoperative anaphylaxis resulting from Lymphazurin 1% blue dye. A 48-year old woman undergoing a mastectomy with sentinel lymph node biopsy experienced a biphasic anaphylactic reaction with two episodes of hypotension at 15 minutes and 2 hou...
متن کاملThe Utility of Serum Tryptase in the Diagnosis of Food-Induced Anaphylaxis
PURPOSE This study investigates the utility of serum tryptase for the confirmation of shrimp-induced anaphylaxis. METHODS Patients with a history of shrimp allergy and positive skin prick tests (SPT) to commercial shrimp extract were recruited for shrimp challenges. Serum total tryptase was obtained at baseline and 60 min (peak) after the onset of symptoms. RESULTS Thirty-nine patients were...
متن کاملPresence or absence of elevated acute total serum tryptase by itself is not a definitive marker for an allergic reaction.
713 March 2015 To the Editor: We read with interest the study by Laroche et al.1 who examined the value of plasma histamine and serum or plasma tryptase in evaluating severe perioperative anaphylaxis. We would like to add some thoughts to further explore and clarify the significance of tryptase as a “predictable marker of allergic reaction.” Indeed, elevated serum total tryptase associated with...
متن کامل[Methylene blue to treat anaphylaxis during anesthesia: case report.].
BACKGROUND AND OBJECTIVES The risk of perioperative anaphylaxis should always be considered. The incidence of anesthetic allergic reactions is controversial, varying from 1/3,000 to 1/20,000, with mortality range between 3 and 9%. This report describes the use of methylene blue as coadjuvant drug to treat anaphylaxis refractory to conventional therapy. CASE REPORT A 53-year-old male patient w...
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BACKGROUND The diagnosis of anaphylaxis is based on clinical history since no reliable biological marker is currently available to confirm the diagnosis. OBJECTIVE It was the aim of this study to determine sequential serum tryptase concentrations during anaphylaxis and to evaluate its potential as a diagnostic marker. METHODS We performed a prospective study including patients with acute an...
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