Factor XI adsorption to surface: interaction of high molecular weight kininogen (HMWK) and a plasma adsorption inhibitor.
نویسندگان
چکیده
منابع مشابه
Immunologic studies of human coagulation factor XI and its complex with high molecular weight kininogen.
Coagulation factor XI was purified from human plasma using ion-exchange chromatography and affinity chromatography on high molecular weight kininogen-Sepharose. A monospecific precipitating antiserum was prepared and used to study factor XI antigen. Factor XI did not migrate during electrophoresis at pH 8.3. High molecular weight kininogen (HMWK), an alpha globulin, reversibly associates with f...
متن کاملProteins involved in the Vroman effect during exposure of human blood plasma to glass and polyethylene.
The amounts of fibrinogen adsorbed to glass from various human blood plasmas have been measured as a function of time. The plasmas were 11 single donor plasmas, pooled plasma, a single donor high molecular weight kininogen (HMWK)-deficient plasma and HMWK-deficient plasma, which had been reconstituted with HMWK. For adsorption times between 1 min and 1 h more fibrinogen adsorbed from HMWK-defic...
متن کاملComplexes Between Cl - Inhibitor , Kallikrein , High Molecular Weight Kininogen , Plasma Thromboplastin
When normal human plasma was adsorbed at 4 C with monosEecific antibody globulins to human Cl -INH inhibitor (anti-Cl -INH). Cl -INH was removed from the plasma in proportion to the amount of antibody globulins used. Clotting activity attributable to Fletcher factor (prekallikreinh high molecular weight kininogen (HMW-K). and irregularly. plasma thromboplastin antecedent (PTA. factor Xl) were a...
متن کاملComplexes Between Cl - Inhibitor , Kallikrein , High Molecular Weight Kininogen
When normal human plasma was adsorbed at 4 C with monosEecific antibody globulins to human Cl -INH inhibitor (anti-Cl -INH). Cl -INH was removed from the plasma in proportion to the amount of antibody globulins used. Clotting activity attributable to Fletcher factor (prekallikreinh high molecular weight kininogen (HMW-K). and irregularly. plasma thromboplastin antecedent (PTA. factor Xl) were a...
متن کاملSurface-mediated defense reactions. The plasma contact activation system.
uring the past two decades, considerable evidence has accrued that many of the body defenses against injury, specifically, blood coagulation, the inflammatory response, classical complement pathway activation, and fibrinolysis, are initiated by a common mechanism. antecedent) have been shown to be the major proteins required to initiate, amplify, and propagate surface-mediated defense reactions...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Blood
دوره 56 2 شماره
صفحات -
تاریخ انتشار 1980