Modifications of lymphocyte subsets in autoimmune thrombocytopenic purpura patients submitted to splenectomy.
نویسندگان
چکیده
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منابع مشابه
A Study of Epidemiology and Therapeutic Response of Patients with Immune Thrombocytopenic Purpura
Background: Immune thrombocytopenic purpura (ITP) is a disease characterized by decrease of the peripheral blood platelet count. The disease presents in acute and chronic forms. Because of the importance and high prevalence of ITP, it was decided to study the therapeutic response of patients with ITP. Material and Methods: A cross-sectional study was conducted at Ghaem hospital, Mashhad, Ira...
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Background: Bernard-Soulier syndrome (BSS) is a rare, autosomal recessive platelet function disorder which is commonly mistaken for idiopathic thrombocytopenic purpura (ITP).The report includes seven cases of BSS that have been diagnosed and treated as ITP for a long time. Methods: Between 2006 and 2016, data of seven BSS patients who have long been diagnosed and treated as ITP were collected ...
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Basis and Objectives: Platelets and/or red blood cells transfusion usually are performed in patients with Immune Thrombocytopenic Purpura (ITP) who are submitted to splenectomy. The purpose of this study is to test if preoperative embolization of splenic artery is able to prevent platelets and/or red blood cells transfusion. Patients and Methods: All patients submitted to splenectomy for purpur...
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A 36 yr-old man of Israeli descent with a history of childhood splenectomy for severe thrombocytopenia and a family history of autoimmune lymphoproliferative syndrome (ALPS), presented with severe immune thrombocytopenic purpura refractory to standard therapy. He was found to possess a heterozygous mutation in the Fas gene (also termed TNFRSF6, CD95, Apo-1) affecting the donor splice site of in...
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Autoimmune thrombocytopenic purpura (AITP) is an autoimmune disorder that results from antiplatelet autoantibodies; these autoantibodies cause platelet destruction in the reticluoendothelial system. Oral corticosteroid therapy is the first line treatment. Splenectomy is the major treatment modality after the failure of more conservative medical therapy. Approximately 15% of the patients will re...
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ورودعنوان ژورنال:
- Haematologica
دوره 85 7 شماره
صفحات -
تاریخ انتشار 2000