Peptide ligation by a reversible and reusable C-terminal thiol handle.
نویسندگان
چکیده
[reaction: see text] Peptide ligation of noncysteinyl residues can be achieved conveniently by a reversible C-terminal thiol handle together with a Ag(+) ion-assisted S,N-acyl migration. The regenerated C-terminal handle permits tandem ligation of multiple segment.
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ورودعنوان ژورنال:
- Organic letters
دوره 7 22 شماره
صفحات -
تاریخ انتشار 2005