Clomiphene Citrate and Oocyte Quality
نویسندگان
چکیده
Ovary is a dynamic organ and generates excess amount of reactive oxygen species (ROS) during follicular growth, development, maturation and ovulation [1]. The increased level of ROS is scavenged by antioxidant systems [2]. A moderate increase of ROS could be beneficial for oocyte meiotic maturation and reproductive outcome [3-5]. Overproduction of ROS or depletion of enzymatic antioxidant systems causes oxidative stress [2].
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Clomiphene Citrate Induces ROS-Mediated Apoptosis in Mammalian Oocytes
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