Enantioselective desymmetrization of prochiral 1,3-dinitropropanes via organocatalytic allylic alkylation.
نویسندگان
چکیده
An enantioselective desymmetrization of prochiral 1,3-dinitropropanes has been developed which proceeds via enantiogroup differentiating organocatalytic allylic alkylation. Densely functionalized products with two vicinal stereocenters were obtained generally with good to excellent diastereoselectivity (up to >20 : 1 dr) and superb enantioselectivity (up to >99 : 1 er).
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 50 1 شماره
صفحات -
تاریخ انتشار 2014