On Executable Models of Molecular Evolution

نویسندگان

  • Marek Kwiatkowski
  • Ian Stark
چکیده

Systems biology can provide unique insights into molecular evolution, but most existing work in this domain uses one-off methods and tools. In this paper, we advocate development of generic frameworks for evolutionary systems biology and discuss in some detail key characteristics it should possess to be most applicable and useful. We offer one such framework ourselves, and evaluate it with a case study of a mitogen-activated protein kinase cascade.

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تاریخ انتشار 2011