2 K kakkad et al (97-103)
نویسندگان
چکیده
histological diagnosis of leprosy patients attending the hospital who consented to undergo slit skin smear (SSS) examination, punch biopsy and participate in the study. Fifty leprosy patients aged 5 to 70 years, which included 41 male and 9 female patients participated in the study. These included 4 TT, 24 BT, 2 BB, 5 BL and 15 LL clinically diagnosed patients as per the IAL classification (1982 ). SSS were undertaken from 4 sites, stained with ZN stain and BI calculated as per Ridley Scale. Four patients were skin smear negative all TT). Of the 24 BT patients enrolled in the study, 11 were skin smear negative while 13 were smear positive (BI ranging from 1+ to 4+); Both the BB cases, all 5 BL cases, and all the 15 LL cases were smear positive (BI range 2+ to 6+). Histologically there was complete parity and correlation in the TT group, while the correlation was observed to be 83%, 50%, 60%, and 93% in the clinically diagnosed BT, BB, BL and LL patients respectively. The sample size in the study was small, however, the overall bacteriological skin smear negativity/positivity correlation was observed to be 53.6% for paucibacillary (TT+BT) disease and 100% for MB (BB, BL and LL) disease Histological correlation was 100%, 83%, 50%, 60% and 93% respectively for clinically diagnosed TT, BT, BB, BL and LL disease. A sizeable number of BT patients were found to be bacteriologically positive and were therefore being treated with lesser number of drugs as well duration under programme conditions. Although there is inter-observer variation and overlapping of clinical and histological diagnosis in the borderline patients (BT, BB & BL), bacteriological and histological confirmation helps in deciding on adequate treatment and should be undertaken.
منابع مشابه
U . S . Patent Dec . 25 , 2012 Sheet 1 of 12 US 8 , 340 , 435 B 2 Calculated weights
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discrimination and reported delay of pharmacy prescriptions and medical tests. J Gen Intern Med 2005;20:578–83. 95 Britt W. Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease. Curr Top Microbiol Immunol 2008;325:417–70. 96 Rosamond W, Flegal K, Furie K et al. Heart disease and stroke statistics—2008 update: a report from the American Heart Associ...
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Background and Objective: The adipokines or adipocytokines are cytokines secreted from adipocyte tissue including Vaspin and chemerin. The purpose of the present study was to investigate the effect of eight weeks of intense aerobic exercise on vaspin and chemerin level changes in female Spraw dawly rats. Materials and Methods: Among the Spraw Dawly rats available in the laboratory of Shiraz Uni...
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