Function and dysfunction of the sphincter of Oddi.
نویسنده
چکیده
In this review, the function of the sphincter of Oddi (SO) is detailed in terms of normal motility, neural and hormonal control of SO function, coordination between gallbladder and SO motility, and correlation of motility of the SO and the duodenum. In addition, SO function tests, such as the morphine Prostigmin test (Nardi test), perfusion manometry, microtransducer manometry, and cholescintigraphy, are explained. Subsequently, the pathophysiology, diagnosis, and treatment of SO dysfunction, including SO stenosis and dyskinesia, are described and discussed in detail. SO manometry and endoscopic sphincterotomy are effective to treat SO dysfunction, but symptoms of the patient must be severe enough to justify these invasive procedures for diagnosis and treatment.
منابع مشابه
Sphincter of Oddi dysfunction produces acute pancreatitis in the possum.
BACKGROUND Sphincter of Oddi dysfunction has been implicated as a cause of various forms of acute pancreatitis. However, there is no direct evidence to show that sphincter of Oddi dysfunction can cause obstruction of trans-sphincteric flow resulting in acute pancreatitis. AIMS To determine if induced sphincter of Oddi spasm can produce trans-sphincteric obstruction and, in combination with st...
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Since its original description by Ruggero Oddi in 1887, the sphincter of Oddi (SO) has been the subject of much study and controversy. Its very existence as a distinct anatomic or physiologic entity has been disputed. Hence, it is not surprising that the clinical syndrome of sphincter of Oddi dysfunction (SOD) and its therapy are controversial areas [1]. Nevertheless, SOD is commonly diagnosed ...
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Sphincter of Oddi dysfunction refers to structural or functional disorders involving the biliary sphincter that may result in impedance of bile and pancreatic juice flow. Up to 20% of patients with continued pain after cholecystectomy and 10–20% of patients with idiopathic recurrent pancreatitis may suffer from sphincter of Oddi dysfunction. This condition is more prevalent among middle-aged wo...
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Ever since its description approximately 100 years ago, the sphincter of Oddi has been surrounded by controversy. First, whether it indeed existed, second, whether it had a significant physiological role in man and more recently whether abnormalities in its function give rise to a clinical syndrome. Data from animal and human studies, using sensitive techniques, have helped define the physiolog...
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عنوان ژورنال:
- Digestive surgery
دوره 27 2 شماره
صفحات -
تاریخ انتشار 2010