harmacokinetic Monitoring of Antiepileptic Drugs
نویسندگان
چکیده
Servicio de Farmacia, Clínica Universitaria, Pamplona, Spain Servicio de Farmacia, Hospital General de Castellón, Castellón, Spain Servicio de Farmacia, Hospital Universitario Reina Sofía, Córdoba, Spain Servicio de Farmacia, Hospital Universitario de Salamanca, Spain Servicio de Farmacia, Hospital San Joan de Déu, Esplugues de Llobregat, Barcelona, Spain Servicio de Farmacia, Hospital Severo Ochoa, Leganés, Madrid, Spain Servicio de Farmacia, Hospital Universitario La Fe, Valencia, Spain Servicio de Farmacia, Hospital General de Alicante, Spain Servicio de Farmacia, Hospital Universitario Dr. Peset, Valencia, Spain Servicio de Farmacia, Hospital Universitario Juan Canalejo, La Coruña, Spain Servicio de Farmacia, Hospital Clínico, Barcelona, Spain
منابع مشابه
Antiepileptic Drugs and Mental Health Status of Patients with Epilepsy
Many patients with epilepsy suffer also from coexisting psychological problems. These mental co-morbidities have a significant impact on quality of life of patients with epilepsy. Recent studies have shown that although antiepileptic drugs (AEDs) treat epilepsy, they may increase risk of mental disorders in these patients . Due to the lack of adequate research in this area, we assess...
متن کاملPharmacokinetic monitoring of antiepileptic drugs.
Monitoring plasma levels of antiepileptic drugs for the treatment and prophylaxis of epilepsy is one of the strategies enabling clinical results to improve by reducing adverse affects and increasing effectiveness. The objective of this article is to review the basic aspects in the monitoring of antiepileptic drugs using a consensus document prepared and endorsed by the pharmacokinetics and phar...
متن کاملP 146: The Best New Antiepileptic Drugs to Prevent Orofacial Malformations as Side Effects of Antiepileptic Drugs
Mothers exposed to Antiepileptic drugs (AEDs) are at high risk to born babies with orofacial malformations such as cleft lips. About 9 percent of congenital abnormalities in babies of mothers with epilepsy relates to orofacial abnormalities. Maintaining safe antiepileptic drugs for millions of mothers with epilepsy is very important. Researches show that new AEDs have less side effects than the...
متن کاملComments on the Eslicarbazepine Acetate Section of the Article ‘Therapeutic Drug Monitoring of the Newer Anti-Epilepsy Medications’
In the past twenty years, 14 new antiepileptic drugs have been approved for use in the United States and/or Europe. These drugs are eslicarbazepine acetate, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, oxcarbazepine, pregabalin, rufinamide, stiripentol, tiagabine, topiramate, vigabatrin and zonisamide. In general, the clinical utility of therapeutic drug monitoring has not bee...
متن کاملAntiepileptic drugs and liver disease
Antiepileptic drugs (AEDs) are no longer restricted to the treatment of epilepsy. These are widely used in a broad spectrum of psychiatric and neurological disorders. Liver plays a major role in the metabolism of a majority of these drugs. Hepatotoxicity is rare, but a real concern when initiating therapy. Likewise, liver disease can adversely affect the biotransformation of some of these drugs...
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