Selective monomethylation of primary amines with simple electrophiles.
نویسندگان
چکیده
Direct monomethylation of primary amines with methyl triflate was achieved with high selectivity (up to 96%). The key point of this single methyl transfer stems from the use of HFIP as the solvent that interferes with amines and avoids overmethylation.
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عنوان ژورنال:
- Chemical communications
دوره 50 15 شماره
صفحات -
تاریخ انتشار 2014