The Treatment of Yaws (frambœsia) with Arsenobenzol (salvarsan)
نویسنده
چکیده
Yaws is a highly contagious and disfiguring disease very prevalent in the tropics and believed now to be caused by a specific spirochaete--the Treponerna pertenuis of Castellani. Although some writers have held that yaws and syphilis are merely two manifestations of the same disease, it can now be stated that the weight of opinion is against' that view and in favor of the view that they are distinct diseases. With this latter conclusion the experimental work of the last few years is in harmony? Monkeys can be inoculated with yaws as with syphilis; and monkeys which have recovered from syphilitic lesions are still susceptible to inoculation with yaws, although they are not reinoculable with syphilis. Moreover. Treponerna pertenuis is distinguishable morphologically f rom Treponerna pallidum; and thus while it can be affirmed that both syphilis and yaws are caused by spiroch~etal organisms, it can also be stated that the spirocha~tm belong to different species. All the evidence is, therefore, to the effect that the diseases are distinct entities. Hitherto, the treatment of yaws has been highly unsatisfactory. In the first place, the usual treatment employed must be continued over long periods of time to attain any permanent result. While this is possible in some cases among the better class of patients, it is nearly impracticable with the class of dispensary and hospital patients, and among the lower classes of natives it is wholly impracticable. There would appear to be no specific treatment for
منابع مشابه
Further Observations on Certain Features of Experimental Syphilis and Yaws in the Rabbit
1. Lesions of the testicle and scrotum of the rabbit produced by the treponema of syphilis and of yaws afford material for the study of chemotherapy, of serum reactions, and of immunity. 2. On experimental and clinical grounds, it appears that yaws can be cured with a smaller dose of salvarsan than is necessary to cure syphilis. 3. The spirochaetae of syphilis do not become resistant after repe...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 13 شماره
صفحات -
تاریخ انتشار 2003