Microbial therapeutics
نویسنده
چکیده
An annotated selection of World Wide Web sites relevant to the topics in microbial biotechnology. Microbiome-therapeutics-Advances-and-challenges_ 2016_Advanced-Drug-Delivery-Reviews.pdf This is a current review on microbial therapeutics. The review discusses additive and subtractive methods for modulating microbiota to improve health. This web page describes a project supported by the National Science Foundation and Microbial Robotics to develop engineered bacteria to release therapeutic chemicals and kill cancer cells. This is a commercial website for a company teaming up with other companies to develop microbial therapeutics. Projects include the treatment of inflammatory bowel disease and Clostridium dificile infections. This review article discusses options for replacing diseased gut microbiota with a healthy gut microbiota to restore health in human
منابع مشابه
Sharpening Host Defenses during Infection: Proteases Cut to the Chase*
The human immune system consists of an intricate network of tightly controlled pathways, where proteases are essential instigators and executioners at multiple levels. Invading microbial pathogens also encode proteases that have evolved to manipulate and dysregulate host proteins, including host proteases during the course of disease. The identification of pathogen proteases as well as their su...
متن کاملIsolation, Characterization and Antimicrobial Activity of Butea monosperma (Lam.)
The root and flowers of Butea monosperma (Lam.) were extracted with methanol. Extensive chromatographic separation and purification with the organic solvents was done. Four phytochemicals were separated and their structures were established based on various spectroscopic techniques. Isolated crude extract was subjected for antibacterial activity against gram-negative and gram-positive bacteri...
متن کاملMicrobiome therapeutics - Advances and challenges.
The microbial community that lives on and in the human body exerts a major impact on human health, from metabolism to immunity. In order to leverage the close associations between microbes and their host, development of therapeutics targeting the microbiota has surged in recent years. Here, we discuss current additive and subtractive strategies to manipulate the microbiota, focusing on bacteria...
متن کاملAntimicrobial Activity of Butea Monosperma Lam. Gum
Gum of Butea monosperma is used to treat microbial and fungal infections in folk medicine. To validate this use, the in- vitro antimicrobial activity of petroleum ether and alcoholic extract of Butea monosperma gum was evaluated against various microbial strains such as Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Salmonella typhimurium , Pseudomonas aeuriogenosa, Esch...
متن کاملApplication of microbial genomic science to advanced therapeutics.
Since the publication of the first complete microbial genome sequence of Haemophilus influenzae in 1995, more than 200 additional microbial genome sequences have become available in the public domain. Approximately 40% of these represent important human pathogens. Comparative in silico methods, along with large-scale approaches such as transcriptomics and proteomics, are beginning to reveal ins...
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