Minimally invasive, imaging guided virtual autopsy compared to conventional autopsy in the foetus, infant and child: study protocol for the paediatric virtual autopsy trial

نویسندگان

  • Christoph Rüegger
  • Christine Bartsch
  • Rosa Maria Martinez
  • Steffen Ross
  • Stephan A. Bolliger
  • Leonhard Schäffer
  • Bernhard Frey
  • Brigitte Koller
  • Leonhard Held
  • Elisabeth Bruder
  • Peter Karl Bode
  • Rosmarie Caduff
  • Hans Ulrich Bucher
چکیده

Department of Neonatology, University Hospital Zurich, Switzerland University Children’s Hospital, Zurich, Switzerland Institute of Forensic Medicine, University of Zurich, Switzerland Division of Obstetrics, University Hospital Zurich, Switzerland Division of Biostatistics, University of Zurich Institute for Pathology, University Hospital Basel, Switzerland Department of Pathology, University Hospital Zurich, Switzerland Corresponding author

منابع مشابه

Minimally invasive, imaging guided virtual autopsy compared to conventional autopsy in foetal, newborn and infant cases: study protocol for the paediatric virtual autopsy trial

BACKGROUND In light of declining autopsy rates around the world, post-mortem MR imaging is a promising alternative to conventional autopsy in the investigation of infant death. A major drawback of this non-invasive autopsy approach is the fact that histopathological and microbiological examination of the tissue is not possible. The objective of this prospective study is to compare the performan...

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ویرتوپسی، مکملی برای اتوپسی

    Background & Aims: A utopsies are recognized as valuable medical procedures. A number of digital radiology techniques, including multislice CT, MRI, and photogrammetry with 3D surface scanning have the potential to change traditional autopsy and improve the reliability of results. Virtual Autopsy is a non-invasive procedure with no damage to the tissues. Noninvasive virtual autopsying could...

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Post mortem magnetic resonance imaging in the fetus, infant and child: A comparative study with conventional autopsy (MaRIAS Protocol)

BACKGROUND Minimally invasive autopsy by post mortem magnetic resonance (MR) imaging has been suggested as an alternative for conventional autopsy in view of the declining consented autopsy rates. However, large prospective studies rigorously evaluating the accuracy of such an approach are lacking. We intend to compare the accuracy of a minimally invasive autopsy approach using post mortem MR i...

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Health professionals' and coroners' views on less invasive perinatal and paediatric autopsy: a qualitative study.

OBJECTIVE To assess health professionals' and coroners' attitudes towards non-minimally and minimally invasive autopsy in the perinatal and paediatric setting. METHODS A qualitative study using semistructured interviews. Data were analysed thematically. RESULTS Twenty-five health professionals (including perinatal/paediatric pathologists and anatomical pathology technologists, obstetricians...

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Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study

BACKGROUND Post-mortem MRI is a potential diagnostic alternative to conventional autopsy, but few large prospective studies have compared its accuracy with that of conventional autopsy. We assessed the accuracy of whole-body, post-mortem MRI for detection of major pathological lesions associated with death in a prospective cohort of fetuses and children. METHODS In this prospective validation...

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تاریخ انتشار 2013