Significance of two skin biopsy performances with consecutive deeper sections in the differential diagnosis between cutaneous polyarteritis nodosa and livedo vasculopathy.

Fig. S1. (A) Purpuric cutaneous nodules on the right sole. (B) Fibrinoid necrosis, admixture of neutrophils and lymphocytes in and around blood vessels, and nuclear dust characteristics of necrotizing vasculitis in the subcutaneous fat were found in the cutaneous nodule on the right sole indicated #1 in (A) by an initial section. (C) Cutaneous nodules and purpuric lesions with livedo in the left lower extremity. (D) Consecutive deeper sections in the skin biopsy specimen in the cutaneous nodule on the left lower extremity indicated #2 in (C). Upper left: an initial section, bottom left: 50th cut, upper right: 100th cut, and bottom right: 150th cut. (E) Necrotizing vasculitis in the 100th deeper section.