Approximate dynamic programming algorithms for optimal dosage decisions in controlled ovarian hyperstimulation

Optimal control of dosage decisions in controlled ovarian hyperstimulation

In the controlled ovarian hyperstimulation (COH) cycle of the in vitro fertilizationembryo transfer (IVF-ET) therapy, the clinicians observe the patients’ responses to gonadotropin dosages through closely monitoring their physiological states, to balance the trade-off between pregnancy rate and ovarian hyperstimulation syndrome (OHSS) risk. In this paper, we model the clinical practice in the C...

Roles of follicle stimulating hormone and luteinizing hormone in controlled ovarian hyperstimulation.

With the advent of recombinant follicle stimulating hormone (FSH) and luteinizing hormone (LH), free from contamination with each other (Loumaye et al., 1995), it is possible to dissect the individual contributions of FSH and LH to the regulation of ovarian function and to define optimal gonadotrophin usage in controlled ovarian hyperstimulation (COH) (Hillier, 1994). Basic and clinical researc...

Effects of Steroid Hormone Levels on the Ultrasound Appearance of the Preovulatory Endometrium in Controlled Hyperstimulation Cycles Ovarian

A DOUBLE BLIND, RANDOMIZED, PLACEBO CONTROLLED STUDY TO ASSESS THE EFFICACY OF KETOCONAZOLE FOR REDUCING THE RISK OF OVARIAN HYPERSTIMULATION SYNDROME

 ABSTRACT Background: In order to evaluate the role ofketoconazole in the prevention of ovarian hyperstimulation syndrome (OHSS) in women with polycystic ovary syndrome (PCOS) undergoing ovarian stimulation with gonadotropins, a prospective, randomized, double-blind, placebo controlled study was done on one-hundred and nine PCOS women that had been refeiTed to be treated by gonadotropi...

A DSS-Based Dynamic Programming for Finding Optimal Markets Using Neural Networks and Pricing

One of the substantial challenges in marketing efforts is determining optimal markets, specifically in market segmentation. The problem is more controversial in electronic commerce and electronic marketing. Consumer behaviour is influenced by different factors and thus varies in different time periods. These dynamic impacts lead to the uncertain behaviour of consumers and therefore harden the t...