Non Heart-Beating Donors in England

Use of non-heart-beating donors in renal transplantation.

The rate of renal transplantation has plateaued and is now limited by the number of donor organs available. In the past all donor kidneys came from living donors or controlled non-heart beating donors. It was not until the introduction of brainstem death criteria that cadaveric heart beating donors became the main source. Recently, there has been renewed interest in non-heart beating donors, wh...

Procurement of liver allografts from non-heart beating donors.

THE shortage of liver allografts continues to be a major limiting factor for the exploitation of liver transplantation. Although satisfactory function of allografts obtained from non-heart beating donors has been reported in kidneys I and livers,2.3 hepatic allografts have been procured almost exclusively from heart -beating donors. 4 •5 The purpose of this study was to determine the safety of ...

The first non-heart-beating organ donor in Hawaii--medical and ethical considerations.

The shortage of organ donors remains a major obstacle in transplantation in Hawaii. Some patients die while waiting for a life-saving organ. Across the nation, "marginal" donors, including non-heart-beating donors are used. The authors describe the first successful non-heart-beating organ donor transplant in Hawaii, and include medical and ethical considerations.

Ex-vivo perfusion and ventilation of rat lungs from non-heart-beating donors before transplant.

BACKGROUND We developed an ex-vivo circuit to evaluate human lungs retrieved from non-heart-beating donors. We assessed the effect of a similar circuit on the function of transplanted rat lungs retrieved from non-heart-beating donors. METHODS One hour after death, Sprague-Dawley rat heart-lung blocks were flushed with 20 mL of cold Perfadex, stored cold for 1 hour, then warmed to 37 degrees C...

Ethical considerations in non-heart beating donation: a narrative review article