DLC1: a tumor suppressor that regulates Rho signaling
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چکیده
منابع مشابه
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Downlo Rho GTPase-activating protein DLC1 is a tumor suppressor that is often deleted in liver cancer and egulated in other cancers. DLC1 regulates the actin cytoskeleton, cell shape, adhesion, migration, and ration through its Rho GTPase-activating protein activity and focal adhesion localization. In this study, nced DLC1 in nonmalignant prostate epithelial cells to explore its tumor suppressi...
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Downlo Rho GTPase-activating protein DLC1 is a tumor suppressor that is often deleted in liver cancer and egulated in other cancers. DLC1 regulates the actin cytoskeleton, cell shape, adhesion, migration, and ration through its Rho GTPase-activating protein activity and focal adhesion localization. In this study, nced DLC1 in nonmalignant prostate epithelial cells to explore its tumor suppressi...
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nloaded Rho GTPase-activating protein DLC1 is a tumor suppressor that is often deleted in liver cancer and egulated in other cancers. DLC1 regulates the actin cytoskeleton, cell shape, adhesion, migration, and ration through its Rho GTPase-activating protein activity and focal adhesion localization. In this study, nced DLC1 in nonmalignant prostate epithelial cells to explore its tumor suppress...
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Deleted in liver cancer (DLC1) is a candidate tumor suppressor gene recently isolated from human hepatocellular carcinoma. Structurally, DLC1 protein contains a conserved GTPase-activating protein for Rho family protein (RhoGAP) domain, which has been thought to regulate the activity of Rho family proteins. Previous studies indicated that DLC1 was frequently inactivated in cancer cells. In the ...
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DLC1 is a candidate tumor suppressor gene recently isolated from human hepatocellular carcinoma (HCC). Structurally, DLC1 protein contains a conserved RhoGAP domain, which has been thought to regulate the activity of Rho family proteins. Previous studies indicated that DLC1 was frequently inactivated in cancer cells. In the present study, we aimed to characterize the tumor suppressor roles of D...
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