Treatment of angiotensin-converting enzyme inhibitor related angioedema with icatibant
نویسندگان
چکیده
Background The absolute risk of angiotensin-converting enzyme (ACE) inhibitor angioedema is 0.3% [1]. The mechanism is felt to be accumulation of bradykinin. The current treatment is discontinuation of ACE-I inhibitor, and intubation if necessary. Icatibant is a bradykinin receptor antagonist, useful in treating hereditary angioedema [2]. We present a patient from a Canadian center who had ACE-inhibitor induced angioedema requiring intubation who did not respond to epinephrine or C1 esterase inhibitor concentrate, then later responded favorably to Icatibant.
منابع مشابه
Treatment of angiotensin receptor blocker-induced angioedema: A case series.
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