Methotrexate Treatment in Children with Febrile Ulceronecrotic Mucha-Habermann Disease: Case Report and Literature Review
نویسندگان
چکیده
Febrile Ulceronecrotic Mucha-Habermann disease is a rare and potentially fatal variant of pityriasis lichenoides et varioliformis acuta and is characterized by high fever, constitutional symptoms, and acute oncet of ulceronecrotic lesions. We present an 11-year-old male with Febrile Ulceronecrotic Mucha-Habermann disease who was cured with methotrexate and review the use of methotrexate for this disorder in the pediatric age group with the relevant literature.
منابع مشابه
Febrile ulceronecrotic Mucha-Habermann disease: a case report and review of the literature.
A 32-year-old male with febrile ulceronecrotic Mucha-Habermann disease (FUMHD) responsive to methotrexate is reported. This is a severe variant of pityriasis lichenoides et varioliformis acuta characterized by the acute onset of a widespread ulceronecrotic cutaneous eruption together with high fever and systemic involvement. To our knowledge, only 13 patients with FUMHD have been reported to date.
متن کاملA fatal case of febrile ulceronecrotic Mucha-Habermann disease in a child
ABS: antibiotics DDS: diamino-diphenyl sulphone FUMHD: Febrile ulceronecrotic MuchaHabermann disease IVIG: intravenous immunoglobulins MI: mucosal involvement MTX: methotrexate PLEVA: pityriasis lichenoides et varioliformis acuta SI: systemic involvement SS: systemic steroids INTRODUCTION Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare, potentially fatal, severe variant of pity...
متن کاملCASE REPORT Febrile ulceronecrotic Mucha–Habermann disease: a case report and a review of the literature
This report describes the case of a 76 year old man who suffered from febrile ulceronecrotic Mucha–Habermann disease (FUMHD). Despite this patient’s typical clinical and histological findings, the fulminating course led to death. Polymerase chain reaction (PCR) analysis of the skin lesions showed that the infiltrating cells were monoclonal in origin and were from an aberrant clone. FUMHD is a v...
متن کاملFebrile ulceronecrotic Mucha–Habermann disease: a case report and a review of the literature
This report describes the case of a 76 year old man who suffered from febrile ulceronecrotic Mucha–Habermann disease (FUMHD). Despite this patient’s typical clinical and histological findings, the fulminating course led to death. Polymerase chain reaction (PCR) analysis of the skin lesions showed that the infiltrating cells were monoclonal in origin and were from an aberrant clone. FUMHD is a v...
متن کاملCASE REPORT Febrile Ulceronecrotic Mucha-Habermann Disease
OBJECTIVE Case report and review of the current literature about febrile ulceronecrotic Mucha-Habermann disease (FUMHD). METHODS Review of our patient's medical records and of the current literature. RESULTS The FUMHD is a rare and potentially lethal type of pityriasis lichenoides et varioliformis acuta. It is characterized by the sudden onset of ulceronecrotic skin lesions associated with ...
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ورودعنوان ژورنال:
دوره 2015 شماره
صفحات -
تاریخ انتشار 2015