Haemangioma with coagulopathy: sustained response to prednisone.
نویسندگان
چکیده
Two cases of giant haemangioma with thrombocytopenia are described. A satisfactory and sustained response to prednisone was achieved in respect of both coagulation abnormalities and tumour size. It is proposed that prednisone is effective by enhancement of thrombosis and reduction of fibrinolysis within the tumour, thus promoting a natural form of resolution. It is suggested that prednisone therapy should be first-choice treatment of complicated haemangiomas.
منابع مشابه
Treatment of a Giant Haemangioma of the Liver With Kasabach-Merritt Syndrome by Orthotopic Liver Transplant
We describe a case of giant cavernous haemangioma of the liver with disseminated intravascular coagulopathy (Kasabach-Merritt syndrome) which was cured by orthotopic liver transplant. A 47 year old man presented with bleeding and tender massive hepatomegaly after tooth extraction. Investigations showed disseminated intravascular coagulopathy and a giant hepatic haemangioma involving both lobes ...
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Haemangioma is a common type of vascular tumour in paediatric age group [1]. Most of them are benign and non-life threatening [1]. Kasabach Merritt syndrome (KMS) is a combination of giant haemangioma, thrombocytopenia and consumptive coagulopathy [1-5]. It presents with diverse clinical presentation and may be a part of other recognized syndrome [1,2]. KMS is a well-recognized but rare clinica...
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Pós-graduando da Seção de Cirurgia Pediátrica. Instituto Nacional de Câncer, Hospital do Câncer I, Rio de Janeiro, RJ Brasil. Médico Cirurgião Pediátrico da Seção de Cirurgia Pediátrica. Instituto Nacional de Câncer, Hospital do Câncer I, Rio de Janeiro, RJ Brasil. Médico Patologista da Seção de Anatomopatologia. Instituto Nacional de Câncer, Hospital do Câncer I, Rio de Janeiro, RJ Brasil. Méd...
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OBJECTIVE To examine the effects of bleomycin A5 on infantile maxillofacial haemangiomas. METHODS Bleomycin A5 was given by multiple intralesinoal injections and the dosage was given according to the age of the patient and size of the lesion. Parts of patients were accompanied by prednisone treatment (2-5 mg/kg, po, QOD. RESULTS All the haemangiomas involutes completely after treated with b...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 50 10 شماره
صفحات -
تاریخ انتشار 1975