Adaptive sequential testing for multiple comparisons.
نویسندگان
چکیده
We propose a Markov process theory-based adaptive sequential testing procedure for multiple comparisons. The procedure can be used for confirmative trials involving multi-comparisons, including dose selection or population enrichment. Dose or subpopulation selection and sample size modification can be made at any interim analysis. Type I error control is exact.
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ورودعنوان ژورنال:
- Journal of biopharmaceutical statistics
دوره 24 5 شماره
صفحات -
تاریخ انتشار 2014