Renal denervation and Symplicity HTN-3: "Dubium sapientiae initium" (doubt is the beginning of wisdom).
نویسندگان
چکیده
Beginning of Wisdom) Renal Denervation and Symplicity HTN-3: ''Dubium Sapientiae Initium'' (Doubt Is the Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2014 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/CIRCRESAHA.115.304099 2014;115:211-214 Circ Res. http://circres.ahajournals.org/content/115/2/211 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Renal denervation for resistant hypertension?
Ever since Schlaich et al.1 first reported on a patient with a blood pressure of 161/107 mm Hg (despite treatment with seven different antihypertensive drugs) that decreased to 127/81 mm Hg after renal denervation, the medical community has been enamored with this procedure. Resistant hypertension evolved into a fashionable diagnosis, and the number of publications pertaining to it grew rapidly...
متن کاملEffect of Catheter-Based Renal Denervation on Morning and Nocturnal Blood Pressure: Insights From SYMPLICITY HTN-3 and SYMPLICITY HTN-Japan.
UNLABELLED High nighttime and early morning blood pressure (BP) have been associated with greater risk for cardiovascular events than high clinic or daytime BP. BP is typically highest in the rising hours, when morning activities typically begin. We examined the effect of renal denervation on morning (6:00-8:59 AM), daytime (9:00 AM-8:59 PM), and nighttime (1:00-5:59 AM) ambulatory BP. Patient ...
متن کاملRenal Denervation for Severe Hypertension: Past, Present and Future
The seventh anniversary of the first catheter-based renal denervation procedure for resistant hypertension is near. At the “end of the beginning”, it is timely to reflect on the next phase in the development and clinical application of renal denervation in hypertension treatment. Unresolved procedural and technical questions are central: To what extent is renal denervation optimal? Is unilatera...
متن کاملSYMPLICITY HTN 3: The death knell for renal denervation in hypertension?
Resistant hypertension is, by definition, a challenge to most physicians treating hypertension. Renal sympathetic denervation has shown promising early results in treating this condition. The SYMPLICITY HTN-3 is the most recent trial to report the effects of this technique on resistant hypertension. This review discusses this study and its surprising neutral results before ending with an overvi...
متن کاملRenal sympathetic denervation for resistant hypertension: Symplicity HTN-3 and the power of placebo
The results of the Symplicity HTN-3 trial have been presented a few days ago in the 2014 Scientific Meeting of the American College of Cardiology and simultaneously published in the New England Journal of Medicine [1]. The Symplicity HTN-3 trial was the first placebo-controlled (via sham procedure) study evaluating the effects of renal sympathetic denervation (RSD) in patients with resistant hy...
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عنوان ژورنال:
- Circulation research
دوره 115 2 شماره
صفحات -
تاریخ انتشار 2014