Regenerative Stem Cells for Endodontic Tissue Engineering: Past, Present and Future

The ultimate aim of endodontic treatment focuses towards the complete preservation of physiologic, structural & mechanical integrity of native pulp – dentin complex. Regenerative endodontic procedure along with tissue engineering can be one of the novel approach to restore tooth structure. Over the last two decades, tissue engineering has promoted from science fiction to science. Tissue engineering & regeneration needs three basics ingredients i.e. morphogenetic signals including growth & differentiation factors, stem cells & a scaffold of extracellular matrix. As all tissues originate from stem cells, these stem cells are the first and utmost important key factor for endodontic regeneration. The present scientific review article is about discussing the basics of stem cells along with their current scenario and future perspectives in endodontic regeneration.