Bier Spots with Characteristic Clinic Presentation: Case Report

Bier spots (BS) were first described in 1898 by Bier and detailed research by Lewis in 1927 [1,2]. There is no certain information about prevalence [2]. It is usually seen in people 20 to 40 years old young adults and is more common in women than man. Pediatric cases were reported [2]. BS are also called physiologic anemic macules, angiospastic macules, exaggerated physiologic speckled mottling of the skin [1]. Clinically the lesions appear as transient, small, white macules with surrounding blanching erythema. Lesions are usually found on the arms and legs [2]. There are some theories about the diseases pathogenesis. BS are thought to be an anatomic and functional damage on little cutaneous vessels dependent on venous hypertension [3]; an exaggerated physiological, vasoconstrictive response induced by venous stasis associated hypoxia [4]; failure of the venoarteriolar reflex in dermal ascending arterioles in dermal ascending arterioles in response to venous filling [5].