Correction for Zurashvili et al., Interaction of PDK1 with Phosphoinositides Is Essential for Neuronal Differentiation but Dispensable for Neuronal Survival.
نویسندگان
چکیده
Tinatin Zurashvili, Lluís Cordón-Barris, Gerard Ruiz-Babot, Xiangyu Zhou, Jose M. Lizcano, Nestor Gómez, Lydia Giménez-Llort, Jose R. Bayascas Institut de Neurociències and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona, Spain; Institut de Neurociències and Departament de Psiquiatria i de Medicina Legal, Universitat Autònoma de Barcelona, Barcelona, Spain
منابع مشابه
Interaction of PDK 1 with phosphoinositides is essential for neuronal 1 differentiation , but dispensable for neuronal survival
23 The 3-phosphoinositide-dependent protein kinase-1 (PDK1) operates in cells in 24 response to phosphoinositide 3-kinase activation and PtdIns(3,4,5)P 3 production by 25 activating a number of AGC kinases, including protein kinase B (PKB)/Akt. Both 26 PDK1 and PKB contain pleckstrin homology domains that interact with the 27 PtdIns(3,4,5)P 3 second messenger. Disrupting the interaction of the ...
متن کاملInteraction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival.
3-Phosphoinositide-dependent protein kinase 1 (PDK1) operates in cells in response to phosphoinositide 3-kinase activation and phosphatidylinositol-3,4,5-trisphosphate [PtdIns(3,4,5)P(3)] production by activating a number of AGC kinases, including protein kinase B (PKB)/Akt. Both PDK1 and PKB contain pleckstrin homology (PH) domains that interact with the PtdIns(3,4,5)P(3) second messenger. Dis...
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Objective(s): Umbilical cord blood-derived mesenchymal stromal cells (UCB-MSCs) are ideally suited for use in various cell-based therapies. We investigated a novel induction protocol (NIP) to improve the neuronal differentiation of human UCB-MSCs under appropriate conditions. Materials and Methods: This experimental study was performed in Iranian Blood Transfusion Organization (IBTO), Tehran, I...
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Purpose: The present study was designed to investigate the effect of different doses of Staurosporine on differentiation of PC-12 cell line into differentiated neuronal cells. Materials and Methods: PC-12 cell line as a useful model system for neurobiological studies was maintained in RPMI 1640 supplemented with 10% FBS. Staurosporine were added to culture medium in different concentrations (1...
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Background & Objective : Bone marrow stromal cells (BMSCs) are a kind of stem cells with high pluripotency. The BMSCs can differentiate into mesodermal and non mesodermal cells. Because of availability of them, they are a suitable source of adult stem cells for cell therapy. Some inducers were used to differentiate stem cells into neural phenotype, such: retinoic acid, dimethyl sulfoxide, dep...
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ورودعنوان ژورنال:
- Molecular and cellular biology
دوره 36 12 شماره
صفحات -
تاریخ انتشار 2016