The insulin - like growth factor - I E - Peptides modulate cell entry of the mature IGF - I protein
نویسندگان
چکیده
Insulin-like growth factor I (IGF-I) is a critical protein for cell development and growth. Alternative splicing of the igf1 gene gives rise to multiple isoforms. In rodents, proIGF-IA and proIGF-IB have different carboxyl-terminal extensions called the E-peptides (EA and EB) and upon further post-translational processing, produce the identical mature
منابع مشابه
The insulin-like growth factor (IGF)-I E-peptides modulate cell entry of the mature IGF-I protein.
Insulin-like growth factor (IGF)-I is a critical protein for cell development and growth. Alternative splicing of the igf1 gene gives rise to multiple isoforms. In rodents, proIGF-IA and proIGF-IB have different carboxy-terminal extensions called the E-peptides (EA and EB) and upon further posttranslational processing, produce the identical mature IGF-I protein. Rodent EB has been reported to h...
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