5,7-Dichloro­quinolin-8-ol

Dichloridobis(5,7-dichloro­quinolin-8-olato-κ2 N,O)tin(IV)

The Sn(IV) atom in the title compound, [Sn(C(9)H(4)Cl(2)NO)(2)Cl(2)], is chelated by the substituted quinolin-8-olate anions in a distorted octa-hedral geometry. The N-donor atoms are in a cis alignment as are the Cl atoms; the O atoms are trans to each other.

Spectrofluorometric determination of erbium in seawater with 5,7-diiodoquinoline-8-ol and rhodamine 6G.

The Fate of the 6a-Hydrogen of 5&holest-7-en-3@ol in the Conversion to 7-Dehydrocholesterol by Rat Liver Microsomes*

2-14C-Mevalonic acid has been incubated with a rat liver homogenate in the presence of the inhibitor frans-1,4bis(2 chlorobenzylaminoethyl) cyclohexanedihydrochloride yielding 1,7,15,22 ,26-14CS-cholesta-5,7-dien3@-01, which was reduced with lithium and ammonia to 14Cs-5ar-cholest-7en-30-01 (A’-cholestanol). Separation from endogenous cholesterol was achieved by oxidation with chromic acid, and...

5,7-Dibromo-2-methyl­quinolin-8-ol

In the title compound, C(10)H(7)Br(2)NO, the mol-ecule possesses a planar geometry with an r.m.s deviation of 0.0383 Å for all non-H atoms. The crystal structure displays O-H⋯N and C-H⋯O hydrogen bonding, as well as Br⋯Br contacts [3.6284 (4) Å].

Palladium-catalysed reactions of 8-hydroxy- and 8-benzyloxy-5,7- diiodoquinoline under aminocarbonylation conditions

Various 5-carboxamido-7-iodo-8-benzyloxyquinolines were synthesised via selective aminocarbonylation of 5,7-diiodo-8-benzyloxyquinoline in the presence of ‘in situ’ generated palladium(0) catalysts. Under similar conditions (50C, 80 bar CO), 5,7-bis(N-tert-butylglyoxylamido)8-hydroxyquinoline was obtained using tert-butylamine as N-nucleophile. The unprotected 5,7-diiodo8-hydroxyquinoline under...