The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors.
نویسندگان
چکیده
The influenza A virus nonstructural NS1 protein is known to modulate host cell gene expression and to inhibit double-stranded RNA (dsRNA)-mediated antiviral responses. Here we identify NS1 as the first viral protein that antagonizes virus- and dsRNA-induced activation of the stress response-signaling pathway mediated through Jun N-terminal kinase.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of virology
دوره 76 21 شماره
صفحات -
تاریخ انتشار 2002