MICs of oxazolidinones for Rhodococcus equi strains isolated from humans and animals.
نویسندگان
چکیده
Eperezolid and linezolid are representatives of a new class of orally active, synthetic antimicrobial agents. The in vitro activity values (MICs) of linezolid, eperezolid, and comparator antibiotics against 102 strains of Rhodococcus equi isolated from humans and animals were determined. Linezolid was more active than eperezolid against the strains tested; premafloxacin was the most active comparator antibiotic.
منابع مشابه
Conjugal transfer of a virulence plasmid in the opportunistic intracellular actinomycete Rhodococcus equi.
Rhodococcus equi is a facultative intracellular, Gram-positive, soilborne actinomycete which can cause severe pyogranulomatous pneumonia with abscessation in young horses (foals) and in immunocompromised people, such as persons with AIDS. All strains of R. equi isolated from foals and approximately a third isolated from humans contain a large, ~81-kb plasmid which is essential for the intramacr...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 44 5 شماره
صفحات -
تاریخ انتشار 2000