The ultrastructure of an abnormal cell in Sézary's syndrome.

S EZARY1 DESCRIBED A SYNDROME manifested by edematous and pigmented erythroderma, leonine facies, lymphadenopathy, and abnormal circulating cells. He considered these abnormal cells to be giant histiocytes which probably originated in the skin, then entered the circulating blood, creating a leukemic state. In this report, the ultrastructural features of the S#{233}zarycell in peripheral blood, lymph nodes, and skin from three patients with S#{233}zary’s syndrome are described.