Quantification of Proteus mirabilis virulence factors and modulation by acylated homoserine lactones.

Salicylic acid reduces the production of several potential virulence factors of Pseudomonas aeruginosa associated with microbial keratitis.

PURPOSE Pseudomonas aeruginosa is a common cause of contact-lens-related microbial keratitis. This bacterium is becoming increasingly resistant to antibiotics, and even if the infection can be treated with antibiotics, damage to the cornea resulting from the combined effect of bacteria and host factors can lead to loss of vision. The purpose of this study was to test the effect of salicylic aci...

Plasmids and Putative Virulence Characters in Proteus mirabilis

Virulence Factors Of Uropathogenic Proteus Mirabilis - A Mini Review

Proteus mirabilis is a common causative agent of the urinary tract. This microorganism expresses several virulence factors. In uropathogenesis processes P. mirabilis can expresses adhesins, flagella, toxins, enzymes, quorum sensing and immune evasion factors. This review describes some aspects of virulence factors of uropathogenic P. mirabilis.

Hybrids of acylated homoserine lactone and nitric oxide donors as inhibitors of quorum sensing and virulence factors in Pseudomonas aeruginosa.

Pseudomonas aeruginosa is an opportunistic pathogen causing a variety of life-threatening diseases such as cystic fibrosis and nosocomial infections in burn victims. The ability of P. aeruginosa to cause infection is attributed to the production of virulence factors such as pyocyanin and elastases. These virulence factors are under the control of quorum sensing (QS) a cell to cell communication...

Reaction of acylated homoserine lactone bacterial signaling molecules with oxidized halogen antimicrobials.

Oxidized halogen antimicrobials, such as hypochlorous and hypobromous acids, have been used extensively for microbial control in industrial systems. Recent discoveries have shown that acylated homoserine lactone cell-to-cell signaling molecules are important for biofilm formation in Pseudomonas aeruginosa, suggesting that biofouling can be controlled by interfering with bacterial cell-to-cell c...