Drug Rediscovery: Preventing Off-label Prescription and Reducing Health Care Costs: The Case of Thioguanine in the Netherlands
نویسندگان
چکیده
We have concerned ourselves at the gastroenterology unit of the VU University Medical Center with drug repositioning since 2001. Generic therapy, often successfully used off-label in daily practice and well described in literature in large observational studies, should be further developed for safe and economically viable use. To prevent off-label use legislative authoritiesshouldstimulate re-registration of these drugs.
منابع مشابه
Drug rediscovery to prevent off-label prescription reduces health care costs: the case of tioguanine in the Netherlands.
We have been concerned with drug rediscovery since 2001 at the Gastroenterology unit of the VU University Medical Center [1]. Generic therapy, o en successfully used off-label in daily practice and well described in the literature in large observational studies, should be further developed for safe and economically viable use. To prevent off-label use but also to encourage scienti c exploration...
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