Mechanism of rhodium-catalyzed carbene formation from diazo compounds.
نویسندگان
چکیده
[reaction: see text] A large and normal nitrogen-15 kinetic isotope effect of 1.035 +/- 0.003 provides direct support for the proposed mechanism for the rhodium-catalyzed carbene formation from diazo compounds, which involves the fast formation of a metal-diazo complex followed by rate-limiting extrusion of N2. The large magnitude of the KIE indicates extensive C-N bond fission in the transition state.
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ورودعنوان ژورنال:
- Organic letters
دوره 9 9 شماره
صفحات -
تاریخ انتشار 2007