Disseminated Bacille Calmette-Guerin (BCG) disease in an infant with severe combined immunodeficiency.

نویسندگان

  • Shagufta Sohail
  • Muhammad Afzal
  • Vaqas Anwar
  • Quratulain Shama
چکیده

Bacille Calmette-Guerin (BCG) vaccine is administered to all newborns in countries where tuberculosis is still endemic. It is a live attenuated vaccine and considered quite safe in immunocompetent children. Disseminated BCG disease is the most serious complication seen only in individuals with underlying primary or secondary immunodeficiencies. We report a case of disseminated BCG disease in an infant with Severe Combined Immunodeficiency (SCID) who received BCG administration prior to diagnosis of SCID.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Author's response to reviews The benefits and risks of bacille Calmette-Guerin vaccination among infants at high risk for both Title: tuberculosis and severe combined immunodeficiency: assessment by Markov model Authors:

The benefits and risks of bacille Calmette-Guerin vaccination among infants at high risk for both Title: tuberculosis and severe combined immunodeficiency: assessment by Markov model

متن کامل

The bone scan pattern in disseminated BCGitis

Despite the long history of the worldwide use of Bacillus Calmette-Guerin (BCG) vaccine, a wide spectrum of adverse reactions has been observed in a small proportion of immunized infants; the most severe complication, disseminated BCGitis, is often fatal but exceedingly rare and is considered to result from host immunodeficiency. At present, CT scan, ultrasound, X-ray and bone marrow aspi...

متن کامل

Post-Vaccination disseminated BCG infection in an 8-month-old infant

Background: Disseminated bacilli calmette-Guerin (BCG) infection after inoculation with live vaccine is considered to result from impaired immunity of the child. However, half of the cases are regarded as idiopathic because no well-defined immunodeficiency condition can account for the infection. Case report: An 8-month-old male infant was admitted with an ulcer on his left arm at the site ...

متن کامل

Disseminated Bacillus Calmette-Guérin Disease after BCG Vaccination: A Case Report from China

Background: Bacillus Calmette-Guérin (BCG) vaccination is recommended for newborn infants worldwide to prevent tuberculosis. However, complications do occur inevitably in a very low rate, among which the most serious is disseminated disease. The disseminated bacillus Calmette–Guérin disease is a rare disease with high fatality, and can be seen among persons with an underlying immunodeficiency. ...

متن کامل

Disseminated BCG disease in an infant with severe combined immunodeficiency

BCG (Bacillus Calmette Guerin) being a live attenuated vaccine may cause disseminated disease (BCGiosis) in patients with impaired immunity. Patients with severe combined immunodeficiency (SCID) having defect in both cellular and humoral immunity are predisposed to a host of live vaccine related complications, especially BCG. We report an infant presenting persistent fever, weight loss, anemia,...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

دوره 24 Suppl 3  شماره 

صفحات  -

تاریخ انتشار 2014