Concepts of similarity in bioinformatics
نویسندگان
چکیده
The key problem of bioinformatics is the prediction of properties, such as structure or function, based on similarity This chapter reviews the concepts and tools of similarity analysis used in various fields of bioinformatics.
منابع مشابه
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Metric information on similarities and distances in fold space is essential for quantitative work in structural bioinformatics and structural biology. Here we derive a suitable metric for protein structures from the fundamental axioms of similarity. Derivation of the metric also clarifies the relationship between the interrelated concepts of distance and similarity.
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