Expression of cyclin D1, p27, p21, bcl-2, and p53 in laryngeal squamous cell carcinoma and an investigation of the correlation with conventional prognostic factors*
نویسندگان
چکیده
Gülçin ŞİMŞEK**, Ünsal HAN, Binnur ÖNAL, Fatma Fulya KÖYBAŞIOĞLU, İstemihan AKIN, Muharrem DAĞLI 1 Department of Pathology, Ministry of Health Ankara Keçiören Training & Research Hospital, 06320 Ankara, Turkey 2 Department of Pathology, Ministry of Health Ankara Dışkapı Training & Research Hospital, 06110 Ankara, Turkey 3 Department of Ear, Nose, and Throat, Ministry of Health Ankara Dışkapı Training & Research Hospital, 06110 Ankara, Turkey
منابع مشابه
Cyclin D1 Expression in Patients with Laryngeal Squamous Cell Carcinoma
Background & Objective: Laryngeal squamous cell carcinoma (LSCC) is considered to be one of the most common cancers of the head and neck, accounting for roughly 90% of all malignant tumors of the larynx. To have a timely diagnosis for a better and practical therapy, molecular markers have to be investigated. The aim of this study was to determine the expression of Cyclin D1 (CD...
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Despite recent improvements in surgical and radiation therapy, failures still occur in patients with laryngeal squamous cell carcinomas, which may have a very different clinical outcome even when their clinical and histopathological characteristics are similar. The apparent inadequacy of "traditional" prognostic factors in predicting the clinical evolution of laryngeal squamous cell carcinomas ...
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