Nuclear Factor-κB Affects Tumor Progression in a Mouse Model of Malignant Pleural Effusion
نویسندگان
چکیده
* Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee. † Pulmonary Division, Saint Thomas Hospital, Nashville, Tennessee. ‡ Department of Pulmonary Medicine, 1 affiliated Hospital of Zhongshan (Sun Yat-sen) University, Guangzhou, Guangdong, P.R. of China. § Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee. ║ Department of Critical Care and Pulmonary Services, Evangelismos Hospital, School of Medicine, University of Athens, Greece. ¶ Department of Veterans Affairs, VA Tennessee Valley Healthcare System, Nashville, Tennessee. ** Vanderbilt Institute of Imaging Science, Department of Radiology and Radiological Sciences, Nashville, Tennessee. †† Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee. AJRCMB Articles in Press. Published on October 6, 2005 as doi:10.1165/rcmb.2005-0130OC
منابع مشابه
Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion.
We developed a novel mouse model of malignant pleural effusion (MPE) by injecting Lewis lung cancer (LLC) cells directly into the pleural space of syngeneic C57B/6 mice. The pleural effusions in this model share common cellular and biochemical features with human MPEs. Implantation and growth of pleural tumors triggers a host inflammatory response characterized by a mixed inflammatory cell infl...
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