FROM BENCH TO BEDSIDE Proteomics and disease: opportunities and challenges
نویسندگان
چکیده
Children’s Cancer Institute Australia for Medical Research, Sydney, NSW. Maria Kavallaris, BAppSc, PhD, Group Leader and NHMRC RD Wright Fellow, Pharmacoproteomics Group, Experimental Therapeutics Program; Glenn M Marshall, MD, FRACP, Head, Molecular Carcinogenesis Program; and Director, Centre for Children’s Cancer and Blood Disorders, Sydney Children’s Hospital, Sydney, NSW. Reprints: Dr Maria Kavallaris, Experimental Therapeutics Program, Children’s Cancer Institute Australia for Medical Research, PO Box 81, Randwick, NSW 2031. [email protected] The Medical Journal of Australia ISSN: 0025729X 6 June 2005 182 11 575-579 ©The Medical Journal of Australia 2005 www.mja.com.au From Bench to Bedside As genomics (the study of genes) has proven predict the structure and dynamic properties of all p field — proteomics — has developed (Box 1). Thi scale study of pr tein expression, structure and funct correlate the structural and functional diversity of underlying biological processes, including disease p teomics has created opportunities to identify, investig
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