Two-color emissive probes for click reactions.

نویسندگان

  • Marcel Wirtz
  • Andreas Grüter
  • Philipp Rebmann
  • Tobias Dier
  • Dietrich A Volmer
  • Volker Huch
  • Gregor Jung
چکیده

Cu(I)-catalyzed azide-alkyne cyclization (CuAAC) is the paradigmatic click reaction of continuous interest. Especially fluorogenic and FRET probes have become indispensable tools for life sciences. Here, we present a fluorescent alkyne for monitoring CuAAC, which undergoes a bathochromic shift upon reaction. Application in single-molecule and catalysis research is foreseen.

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عنوان ژورنال:
  • Chemical communications

دوره 50 84  شماره 

صفحات  -

تاریخ انتشار 2014