Commentary on "spasticity or reversible muscle hypertonia?".
نویسندگان
چکیده
منابع مشابه
Spasticity and Its Contribution to Hypertonia in Cerebral Palsy
Spasticity is considered an important neural contributor to muscle hypertonia in children with cerebral palsy (CP). It is most often treated with antispasticity medication, such as Botulinum Toxin-A. However, treatment response is highly variable. Part of this variability may be due to the inability of clinical tests to differentiate between the neural (e.g., spasticity) and nonneural (e.g., so...
متن کاملOptical inhibition of motor nerve and muscle activity in vivo.
INTRODUCTION There is no therapeutic approach that provides precise and rapidly reversible inhibition of motor nerve and muscle activity for treatment of spastic hypertonia. METHODS We used optogenetics to demonstrate precise and rapidly reversible light-mediated inhibition of motor nerve and muscle activity in vivo in transgenic Thy1::eNpHR2.0 mice. RESULTS We found optical inhibition of m...
متن کاملSpasticity or reversible muscle hypertonia?
BACKGROUND AND OBJECTIVE The increase in resistance to passive muscle stretch in a paretic limb due to an upper motor neurone lesion is often referred to as muscle spasticity. However, this terminology is inaccurate and does not take into account the complex pathogenesis of the condition or describe the factors that contribute to the clinically observed changes in muscle tone. In this report we...
متن کاملPathophysiology of Spasticity: Implications for Neurorehabilitation
Spasticity is the velocity-dependent increase in muscle tone due to the exaggeration of stretch reflex. It is only one of the several components of the upper motor neuron syndrome (UMNS). The central lesion causing the UMNS disrupts the balance of supraspinal inhibitory and excitatory inputs directed to the spinal cord, leading to a state of disinhibition of the stretch reflex. However, the del...
متن کاملSpasticity and muscle contracture following stroke.
It has become increasingly recognized that the major functional deficits following brain damage are largely due to "negative' features such as weakness and loss of dexterity rather than spasticity. A variety of studies suggest that spasticity is a distinct problem and separate from the loss of dexterity, but that it may be implicated in the formation of muscle contracture and even in the recove...
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ورودعنوان ژورنال:
- Journal of rehabilitation medicine
دوره 43 9 شماره
صفحات -
تاریخ انتشار 2011