Contrast-Enhanced MRA in the NSF Era: Potential for Contrast Dose Reduction
نویسنده
چکیده
Purpose: Higher doses of gadolinium-based contrast agents (GBCA) are often used for contrast-enhanced MRA (CE-MRA). Patients with moderateto-severe (stages 3-5) chronic kidney disease undergoing contrast-enhanced MR imaging are known to be at increased risk for developing nephrogenic systemic fibrosis, particularly with higher doses or repeated exposure to GBCA (1-2). Herein we review information on the application of lower doses of the higher-relaxivity gadobenate dimeglumine (MultiHance; Gd-BOPTA) for CE-MRA.
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