Neurofibromatosis, gigantism, elephantiasis neuromatosa and recurrent massive subperiosteal hematoma: a new case report and review of 7 case reports from the literature.

Giant elephantiasis neuromatosa in the setting of neurofibromatosis type 1: A case report.

Elephantiasis neuromatosa (EN) can arise from a plexiform neurofibroma of the superficial and deep nerves developing from a hyperproliferation of the perineural connective tissue infiltrating adjacent fat and muscles. To date, the clinical association between EN and neurofibromatosis type 1 (NF1) has been poorly defined, particularly with regard to the role of lymphatic alterations and the cons...

Nodular fibrosis in non-Filarial Elephantiasis: A case report

Epidermal changes including hyperkeratosis and epidermal verrucous changes, papillomatosis, secondary infection, recurrent erysipelas and ulceration are complications of chronic lymphedema. Elephantiasis is a term used for these significant changes. Xanthoma may also develop in lymphedematous areas. Lymphangiosarcoma is a rare complication of chronic lymphedema. Nodular fibrosis is mentioned as...

TUMOR ASSOCIATED OSTEOMALACIA IN NEUROFIBROMATOSIS: CASE REPORT AND LITERATURE REVIEW

The association of osteomalacia with neurofibromatosis is a very rare entity. Here a 34 year old man, a known case of neurofibromatosis, is reported who presented with bone pain, hypophosphatemia, rena] phosphorus wasting, multiple Looser's pseudofractures, and low bone density. Treatment with high dose calcitriol and phosphate resulted in temporary treatment. Permanent cure was achieved a...

NEUROFIBROMATOSIS PRESENTING AS SCROTAL ELEPHANTI ASIS

Neurofibromatosis being manifested as scrotal elephantiasis is a very rare condition and in review of the literature no such presentation was found. Here we report a 20 year old man who presented with scrotal elephantiasis and consequently, a pathological diagnosis of neurofibromatosis was reached.

Neurofibromatosis, gigantism and subperiosteal haematoma. Report of two children with extensive subperiosteal bone formation.