Methyl ethyl ketone peroxide

A case of severe corrosive esophagitis, gastritis, and liver necrosis caused by ingestion of methyl ethyl ketone peroxide

The plastic hardener methyl ethyl ketone peroxide is unstable peroxide that releases free oxygen radicals. Ingestion of this compound induces widespread liver necrosis, severe metabolic acidosis, corrosive esophagitis and gastritis, that is often fatal. A 49-year-old man unintentionally ingested approximately 100 mL (55%) of this compound in solution, which was purchased as plastic hardener. De...

Abatement of Benzyl Alcohol and Methyl Ethyl Ketone (MEK) from Polluted Air Over Nanostructured Mn -Supported Alumina Catalyst

[An organic peroxide, methyl ethyl ketone peroxide, damage to cytochrome P-450 peroxidase and microsomal enzymes activity].

In vivo, an organic peroxide, methyl ethyl ketone peroxide (MEKP) damaged microsomal cytochrome P-450 and cytochrome P-450 peroxidase in vitamin E deficient rat livers. Dietary vitamin E protected the microsomal enzymes from MEKP damage. Phenobarbital induced liver cytochrome P-450 peroxidase and glutation S-transferase and decreased MEKP damage on microsomal enzymes. MEKP induced production of...

A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management

Methyl Ethyl Ketone Peroxide (MEKP) is a highly toxic clear liquid used as a solvent. It is a strong oxidizing agent and a corrosive. Acute and chronic toxicity can occur as an occupational hazard. Ingestion is associated with corrosive burns leading to stricture formation, inhalational pneumonitis, acidosis, liver failure and renal failure. In this paper we present a case of a young patient wh...

Thermal Hazard Analysis of Methyl Ethyl Ketone Peroxide

In the past forty years in Japan and Taiwan, many thermal explosions have been caused by methyl ethyl ketone peroxide (MEKPO) under the influence of external fire and others. Thermograms of commercialized MEKPO dimers were first screened by Differential Scanning Calorimetry (DSC) to determine the heat of decomposition and exothermic onset temperature. Thermal runaway phenomena were then thoroug...