PM521. Relationship between Negative Symptoms and Social Cognition in Patient with Schizophrenia

s | 89 needs to address and be informed by complex interactions with cannabis usage. PM520 Association between Schizophrenia and Urinary Incontinence: A Population-Based Study Running title: Urinary Incontinence and Schizophrenia Wen-Yu Hsu, MD Chih-Hsin Muo, MS Szu-Pin Ma, MD Chia-Hung Kao, MD Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan (W-Y Hsu);Department of Psychiatry, Changhua Christian Hospital, Changhua, Taiwan (W-Y Hsu, S-P Ma); School of Medicine, Chung Shan Medical University, Taichung, Taiwan (W-Y Hsu); Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan (C-H Muo); Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan (C-H Kao); Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan (C-H Kao) Abstract Objective: Urinary incontinence (UI) is defined as the involuntary loss of urine and can constitute a hygiene or social problem for affected patients. Whether the UI incidence is higher in patients with schizophrenia than in the general population remains undetermined. Methods: The patients in this population-based cohort study were selected from the Taiwan National Health Insurance Research Database, using claims data from 2005 to 2011. We compared the incidence of UI between schizophrenia and nonschizophrenia cohorts. Cox proportional hazards regression models were employed for analyzing the risk of UI after adjustment for sex, age, and comorbidities. Results: The adjusted hazard ratio for UI in the schizophrenia cohort was 1.78-fold higher than that in the nonschizophrenia cohort. Furthermore, male patients with schizophrenia were more susceptible to UI than their female counterparts, and a higher risk of UI was observed among younger patients with schizophrenia. Conclusion: Compared with the general population, the risk of UI was higher among the patients with schizophrenia. Early diagnosis and intervention can increase the quality of life among patients with schizophrenia.